On the other hand, non alcoholic FLD may begin as excess of
Defects in fatty acid metabolism are responsible for pathogenesis of FLD, which may be due to imbalance in energy consumption and its combustion, resulting in lipid storage, or can be a consequence of peripheral resistance to insulin, whereby the transport of fatty acids from adipose tissue to the liver is increased.[1][12] Impairment or inhibition of receptor molecules (PPAR , PPAR and SREBP1) that control the enzymes responsible for the oxidation and synthesis of fatty acids appears to contribute to fat accumulation. In addition http://www.canadagoose17.top/, alcoholism is known to damage mitochondria and other cellular structures, further impairing cellular energy mechanism. On the other hand, non alcoholic FLD may begin as excess of unmetabolised energy in liver cells.
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